Jump to ContentJump to Main Navigation
Meselson, Stahl, and the Replication of DNAA History of "The Most Beautiful Experiment in Biology"$
Users without a subscription are not able to see the full content.

Frederic Lawrence Holmes

Print publication date: 2001

Print ISBN-13: 9780300085402

Published to Yale Scholarship Online: October 2013

DOI: 10.12987/yale/9780300085402.001.0001

Show Summary Details
Page of

PRINTED FROM YALE SCHOLARSHIP ONLINE (www.yale.universitypressscholarship.com). (c) Copyright Yale University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in YSO for personal use.date: 25 September 2021

The Subunits of Semiconservative Replication

The Subunits of Semiconservative Replication

Chapter:
(p.388) Chapter Twelve The Subunits of Semiconservative Replication
Source:
Meselson, Stahl, and the Replication of DNA
Author(s):

Frederic Lawrence Holmes

Publisher:
Yale University Press
DOI:10.12987/yale/9780300085402.003.0013

This chapter describes the immediate impact the publication of the Meselson-Stahl experiment in PNAS had on the circle of biologists already engaged with the replication of DNA, and how it extended well beyond that circle. Within the group who had participated in or followed the debate over conservative, semiconservative, and dispersive replication, it was rapidly accepted that Meselson and Stahl's experiment settled the question in favor of semiconservative replication but did not immediately confirm the Watson-Crick prediction that the molecule replicated by separation of the two nucleotide strands constituted a double helix. Meselson and Stahl themselves contributed to this ambiguity in a paper on the replication of DNA that they gave at a session titled “Replication and Recombination of Genetic Material” at the Cold Spring Harbor Symposium held in June 1958.

Keywords:   Meselson-Stahl experiment, PNAS, circle of biologists, replication of DNA, semiconservative replication, nucleotide strands, double helix

Yale Scholarship Online requires a subscription or purchase to access the full text of books within the service. Public users can however freely search the site and view the abstracts and keywords for each book and chapter.

Please, subscribe or login to access full text content.

If you think you should have access to this title, please contact your librarian.

To troubleshoot, please check our FAQs , and if you can't find the answer there, please contact us.