Jump to ContentJump to Main Navigation
Meselson, Stahl, and the Replication of DNA – A History of "The Most Beautiful Experiment in Biology" - Yale Scholarship Online
Users without a subscription are not able to see the full content.

Meselson, Stahl, and the Replication of DNA: A History of "The Most Beautiful Experiment in Biology"

Frederic Lawrence Holmes


In 1957, two young scientists, Matthew Meselson and Frank Stahl, produced a landmark experiment confirming that DNA replicates as predicted by the double helix structure Watson and Crick had recently proposed. It also gained immediate renown as a “most beautiful” experiment whose beauty was tied to its simplicity. Yet the investigative path that led to the experiment was anything but simple. This book vividly reconstructs the complex route that led to the Meselson-Stahl experiment and provides an inside view of day-to-day scientific research—its unpredictability, excitement, intellectual chall ... More

Keywords: Matthew Meselson, Frank Stahl, DNA, double helix, scientific research, unpredictability, excitement, intellectual challenge, Watson, Crick

Bibliographic Information

Print publication date: 2001 Print ISBN-13: 9780300085402
Published to Yale Scholarship Online: October 2013 DOI:10.12987/yale/9780300085402.001.0001


Affiliations are at time of print publication.

Frederic Lawrence Holmes, author