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Quantitative Evaluation of HIV Prevention Programs$
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Edward H. Kaplan and Ron Brookmeyer

Print publication date: 2001

Print ISBN-13: 9780300087512

Published to Yale Scholarship Online: October 2013

DOI: 10.12987/yale/9780300087512.001.0001

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Design of HIV Trials for Estimating External Effects

Design of HIV Trials for Estimating External Effects

Chapter:
(p.223) Chapter 11 Design of HIV Trials for Estimating External Effects
Source:
Quantitative Evaluation of HIV Prevention Programs
Author(s):

Tomas Philipson

Publisher:
Yale University Press
DOI:10.12987/yale/9780300087512.003.0012

This chapter examines the importance of external effects for the purpose of evaluating and designing HIV prevention trials. It illustrates and defines private effects (in the vaccine example, protection offered by the vaccine itself) and external effects (which would be induced by the number of persons vaccinated in the population). The chapter also proposes a two-step randomization process for identifying these effects, and illustrates them in the context of HIV prevention trials conducted in Africa.

Keywords:   HIV prevention, private effect, vaccine, external effects, randomization process, HIV prevention trials, Africa

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