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Quantitative Evaluation of HIV Prevention Programs$
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Edward H. Kaplan and Ron Brookmeyer

Print publication date: 2001

Print ISBN-13: 9780300087512

Published to Yale Scholarship Online: October 2013

DOI: 10.12987/yale/9780300087512.001.0001

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Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines

Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines

(p.241) Chapter 12 Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines
Quantitative Evaluation of HIV Prevention Programs

Ira M. Longini Jr.

Michael G. Hudgens

M. Elizabeth Halloran

Yale University Press

This chapter proposes a research design for estimating the protective effects of prophylactic vaccines. Following the structure of the HIV vaccine trial of the Bangkok Metropolitan Administration cohort of injecting drug users (IDUS), the chapter simulates HIV transmission within this trial structure to investigate whether the proposed design is sufficiently powerful to estimate vaccine efficacy.

Keywords:   prophylactic vaccines, HIV vaccine trial, Bangkok Metropolitan Administration, injecting drug users, IDUS, HIV transmission, vaccine efficacy

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