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Quantitative Evaluation of HIV Prevention Programs$
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Edward H. Kaplan and Ron Brookmeyer

Print publication date: 2001

Print ISBN-13: 9780300087512

Published to Yale Scholarship Online: October 2013

DOI: 10.12987/yale/9780300087512.001.0001

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PRINTED FROM YALE SCHOLARSHIP ONLINE (www.yale.universitypressscholarship.com). (c) Copyright Yale University Press, 2021. All Rights Reserved. An individual user may print out a PDF of a single chapter of a monograph in YSO for personal use.date: 24 June 2021

Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines

Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines

Chapter:
(p.241) Chapter 12 Estimation of Vaccine Efficacy for Prophylactic HIV Vaccines
Source:
Quantitative Evaluation of HIV Prevention Programs
Author(s):

Ira M. Longini Jr.

Michael G. Hudgens

M. Elizabeth Halloran

Publisher:
Yale University Press
DOI:10.12987/yale/9780300087512.003.0013

This chapter proposes a research design for estimating the protective effects of prophylactic vaccines. Following the structure of the HIV vaccine trial of the Bangkok Metropolitan Administration cohort of injecting drug users (IDUS), the chapter simulates HIV transmission within this trial structure to investigate whether the proposed design is sufficiently powerful to estimate vaccine efficacy.

Keywords:   prophylactic vaccines, HIV vaccine trial, Bangkok Metropolitan Administration, injecting drug users, IDUS, HIV transmission, vaccine efficacy

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