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Science as AutobiographyThe Troubled Life of Niels Jern$
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Thomas Soderqvist

Print publication date: 2003

Print ISBN-13: 9780300094411

Published to Yale Scholarship Online: October 2013

DOI: 10.12987/yale/9780300094411.001.0001

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“Antibody This, Antibody That, They Weren't Really Much Interested”

“Antibody This, Antibody That, They Weren't Really Much Interested”

Chapter:
(p.133) 12 “Antibody This, Antibody That, They Weren't Really Much Interested”
Source:
Science as Autobiography
Author(s):

Thomas Söderqvist

Publisher:
Yale University Press
DOI:10.12987/yale/9780300094411.003.0012

This chapter shows Ole Maaloe heading full-speed into a study of bacteriophages, that is, viruses that infect and replicate in bacterial cells, while Niels Jerne was beginning to identify himself as an immunologist. Max Delbruck and other geneticists used the tiny phage as a model organism to understand the molecular mechanism of heredity, and during his stay at Cal Tech in the spring of 1949, Maaloe had been seriously bitten by the “phage bug.” He returned to Copenhagen full of energy and ideas and, with Orskov's indulgence, established his one-man branch of the internationally dispersed phage group in the Standardization Department. The following spring he started a series of experiments on how changes in temperature affect the reproduction of phages in the bacterial cell.

Keywords:   bacteriophages, Ole Maaloe, Niels Jerne, bacterial cells, immunologist, Max Delbruck, Cal Tech, heredity

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